By Robert Preidt
THURSDAY, Oct. 26, 2017 (HealthDay News) — Blood thinners may pull double obligation for individuals with the heart beat clutter atrial fibrillation: New investigate suggests they offer assistance prevent dementia as well as stroke.
Because atrial fibrillation increases the risk for stroke, individuals with the condition are often prescribed blood thinners (also known as anticoagulants) to anticipate blood clots that can cause a stroke.
Atrial fibrillation also increases the chance for dementia. Amid the ponder, more than 26,000 of the 440,000 participants, all with atrial fibrillation, were diagnosed with dementia.
At the time they joined the consider, about half of the participants were taking oral anticoagulants, such as warfarin, Eliquis (apixaban), Pradaxa (dabigatran), Savaysa (edoxaban) or Xarelto (rivaroxaban).
The researchers found that people taking anticoagulants were 29 percent less likely to create dementia than were those who were not taking the blood thinners.
When the researchers centered on people who proceeded to take the drugs, they found an even larger reduction (48 percent) in the hazard for dementia. They too found that the sooner individuals begun taking blood thinners after their conclusion of atrial fibrillation, the lower their chance for dementia.
Along with not taking blood thinners, the strongest predictors for dementia were age, Parkinson’s infection and liquor manhandle, agreeing to the ponder, published Oct. 25 in the European Heart Journal.
The findings strongly suggest that blood thinners reduce the hazard for dementia in individuals with atrial fibrillation, but proving that would not be possible, the Swedish analysts said.
“In order to prove this suspicion, randomized placebo-controlled trials would be required, but such ponders cannot be done because of moral reasons,” analysts Leif Friberg and Marten Rosenqvist, of the Karolinska Established in Stockholm, said in a journal news discharge. “It is not possible to deliver fake treatment to [atrial fibrillation] patients and then wait for dementia or stroke to occur.”
In any case, the findings show that people with atrial fibrillation ought to begin taking blood thinners as soon as possible after their diagnosis and continue to take the drugs, Friberg famous.
“Patients start on verbal anticoagulation for stroke anticipation but they halt after many years at an alarmingly high rate,” he said. “Within the first year, approximately 15 percent stop taking the drugs, then around 10 percent each year.”
“In case you know that [atrial fibrillation] eats absent your brain at a slow but consistent pace and that you can avoid it by remaining on treatment, I think most patients would discover this a very strong argument for proceeding treatment,” he said.